hrp0089p2-p149 | Fat, Metabolism and Obesity P2 | ESPE2018

Galanin is Positively Correlated with Insulin Resistance and Triglyceride Levels in Obese Children

Acar Sezer , Paketci Ahu , Kume Tuncay , Demir Korcan , Calan Ozlem Gursoy , Bober Ece , Abacı Ayhan

Introduction: Galanin is a neuropeptide involved in the regulation of food intake and glucose homeostasis. The objective of this study was to assess the relation of serum galanin levels with anthropometric and metabolic parameters in obese and healthy children.Material and methods: This cross-sectional study consisted of 38 obese children (mean age, 11.9±3.0 years) and 30 healthy children (mean age, 11.4±2.0 years). Clinical and biochemical [gl...

hrp0084p2-358 | Fat | ESPE2015

Elevated Serum Irisin Level is not Related to Metabolic and Anthropometric Parameters in Obese Children

Abaci Ayhan , Catli Gonul , Tuhan Hale Unver , Anik Ahmet , Kume Tuncay , Calan Ozlem Gursoy , Bober Ece

Background: Irisin is a newly discovered myokine which regulates energy metabolism and obesity (type 2 diabetes pathogenesis). However, results of the clinical studies investigating the relation of irisin with metabolic and anthropometric parameters remain controversial, and studies in obese children are limited.Objective and hypotheses: We aimed to investigate the relation of serum irisin level with metabolic and anthropometric parameters in obese child...

hrp0089p2-p395 | Thyroid P2 | ESPE2018

Serum Level of Biotin Rather than the Daily Dose is the Main Determinant of the Interference on Thyroid Function Assays in Patients with Biotinidase Deficiency

Paketci Ahu , Kose Engin , Calan Ozlem Gursoy , Acar Sezer , Teke Pelin , Demirci Ferhat , Abacı Ayhan , Demir Korcan , Arslan Nur , Bober Ece

Introduction: High doses of biotin are reported to cause incorrect results in various immunoassays in some patients. However, there is no systematic study regarding biotin interference in childhood.Aim: To assess thyroid function with different methods in subjects with biotinidase deficiency, to determine the factors causing interference, and to investigate the efficiency of the methods for overcoming interference.Method: The study...